Case：Allergy / Immunity
The results of a collaborative research with Kinki University have been published in the Natural Product Communications.
We conducted a study to evaluate the anti-allergic property of the OM-X extract by using cell and mouse models which is an index of the type I allergy, including asthma and hay fever.
For the evaluation of the anti-allergic property of the OM-X extract, we examined the action of the OM-X extract by looking at the degranulation on rat basophilic leukemia cells (RBL-2H3) which is a model of mast cell and passive cutaneous anaphylaxis reaction (PCA) on mouse models of the type I allergy.
<The inhibitory effect against the degranulation of RBL-2H3 cells>
The degranulation that provokes allergic reactions was inhibited in a dose-dependent manner of the OM-X extract.
<The inhibitory effect against the type I allergy (mice)>
aspect of PCA reaction in mouse models of the type I allergy, the degree of
pigmentation decreased and the allergic reactions were suppressed by an
ingestion of the OM-X extract.
Last updated 2017/02/23