It is known that antioxidant capacity decreases in a mouse incapable of synthesizing vitamin C within its body, and in turn its hepatic function deteriorates.
administered one of these mice OM-X, and measured the numerical numbers (AST,
ALT) of each one. These numbers become higher in accordance with the ingravescence of hepatic function. The transaminase level
increased considerably in a vitamin C synthesis insufficient mouse, compared to
a normal one. On the other hand, the level did not increase significantly in the
vitamin C synthesis insufficient mouse with OM-X administration. The result of
metabolome analysis on liver showed that administering OM-X suppresses
intravital oxidation of mice and a decrease of ATP producibility.
Last updated 2018/07/26