Congress & Meeting



The 138th Annual Meeting of the Pharmaceutical Society of Japan (Kanazawa)

Date 2018/07/26

Study on protective action of hepatic function using Fermented Vegetable Extract (OM-X)

It is known that antioxidant capacity decreases in a mouse incapable of synthesizing vitamin C within its body, and in turn its hepatic function deteriorates.

We administered one of these mice OM-X, and measured the numerical numbers (AST, ALT) of each one. These numbers become higher in accordance with the ingravescence of hepatic function. The transaminase level increased considerably in a vitamin C synthesis insufficient mouse, compared to a normal one. On the other hand, the level did not increase significantly in the vitamin C synthesis insufficient mouse with OM-X administration. The result of metabolome analysis on liver showed that administering OM-X suppresses intravital oxidation of mice and a decrease of ATP producibility.


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